The Arthritis Foundation is boldly pursuing a cure for America's #1 cause of disability, while championing the fight against arthritis with life-changing resources, science, advocacy and community connections. The Arthritis Foundation’s Jingle Bell Run is the nation’s original festive race for charity. Taking place in almost 100 cities nationwide, Jingle Bell Run raises funds to benefit the more than 54 million Americans (1 in 4 adults), including 300,000 children (1 in every 250) living with arthritis pain every day. From funding cutting-edge research for new treatments and ultimately a cure to advocating for health care access, the Arthritis Foundation helps those living with arthritis score everyday victories, one step at a time.

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Big Cat Rescue

Big Cat Rescue in Tampa, Florida is one of the largest accredited sanctuaries for exotic cats in the world. The sanctuary is home to approximately 70 big cats, most of whom were abandoned or neglected by owners who mistakenly thought they made good pets, abused, seized by authorities, orphaned or retired from performing acts. The sanctuary’s mission is to provide the best home for the cats in their care, end abuse of big cats in captivity and prevent extinction of big cats in the wild.

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Alex's Lemonade Stand

Alex's Lemonade Stand Foundation emerged from the front yard lemonade stand of cancer patient Alexandra “Alex” Scott (1996-2004). Since Alex set up her first stand, the foundation bearing her name has evolved into a national fundraising movement dedicated to funding critically needed medical research to find effective treatments and cures for childhood cancer. From the time of its inception, ALSF has successfully raised more than $150 million and funded over 800 cutting-edge research projects. In addition, the foundation has awarded numerous nursing and psychosocial grants to improve the quality of life and care of children with cancer and their families.

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Toys for Tots

Toys for Tots, a 70-year national charitable program run by the U.S. Marine Corps Reserve, provides happiness and hope to disadvantaged children during each Christmas holiday season. The toys, books and other gifts collected and distributed by the Marines offer these children recognition, confidence and a positive memory for a lifetime. It is such experiences that help children become responsible citizens and caring members of their community. Last year the Marine Toys for Tots Program fulfilled the holiday hopes and dreams of 7 million less fortunate children in 792 communities nationwide. Since 1947 over 244 million children have been assisted.

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Conservation Nation

Conservation Nation raises funds to support the global network of Smithsonian scientists and researchers working to save threatened and endangered species. Conservation Nation is currently funding conservation projects for five different species in five different countries: Asian elephants in Myanmar, reticulated giraffes in Kenya, harlequin frogs in Panama, scimitar-horned oryx in Chad, and red siskins in Venezuela. Wildlife conservation isn’t easy, but together, we can help erase extinction.